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Receptors of Cell Adhesion and Cellular Recognition, Volume 3

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Data Lançamento:
05/02/2015
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Sinopse

Volume 3 of Biomembranes covers receptors of cell adhesion and cellular recognition. Proteins in the plasma membrane of cells are heavily involved in processes of cell adhesion, but such proteins were not actually isolated and characterized until the mid-1970s. Since then, application of the methods of molecular biology has led to the recognition of four major classes of cell adhesion molecule (CAMs), the immunoglobulin super family, the cadherins, the integrins, and the selecting. A convenientsystem in which to study the importance of cell adhesion is in blood platelets where aggregation eventually leads to thrombus formation in a process involving a range of surface glycoproteins. Interaction with the extracellular matrix is exemplifiedby CD44, the receptor for hyaluronan, and a complex carbohydrate that is a major component of the extracellular matrix surrounding migrating and proliferating cells. Membrane-associated mucins have a variety of effects on cell adhesion. The super family of immunoglobulin related proteins also include the T cell receptors and the major histocompatibility complex (MHC), which, together with the receptors for immunoglobulins (the Fc receptors), are of fundamental importance in the processes of immunity. Volume 3 of Biomembranes explores the structures and functions of the molecules involved in these important functions of the cell.<br>

Ficha técnica

Código de barras:
9781559386609
Dimensões:
25.00cm x 19.00cm x 1.00cm
Marca:
ELSEVIER SCIENCE USA
Idioma:
Inglês
ISBN13:
9781559386609
Número de páginas:
319
Peso:
2.000 kg
Ano de publicação:
2015
Encadernação:
Capa Dura