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Protein Folding in Silico

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Por: R$ 781,00 Em 2x de: R$ 390,50 No boleto: R$ 781,00

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Data Lançamento:
05/02/2015
Prazo de entrega de 70 dias
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Sinopse

Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silicoapproaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the "fuzzy oil drop" model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks.<ul><li>Discusses a range of ab initio models for protein structure prediction</li><li>Introduces a unique model based on experimental observations</li><li>Describes various methods for the quantitative assessment of the presented models from the viewpoint of information theory</li></ul>

Ficha técnica

Código de barras:
9781907568176
Dimensões:
25.00cm x 19.00cm x 1.00cm
Marca:
Woodhead Publishing Limited
Idioma:
Inglês
ISBN13:
9781907568176
Número de páginas:
240
Peso:
2.000 kg
Ano de publicação:
2015
Encadernação:
Capa Dura